About half of them are depressed. Or at least that is the diagnosis that they got when they were put on antidepressants. . . . They go to work but they are unhappy and uncomfortable; they are somewhat anxious; they are tired; they have various physical pains—and they tend to obsess about the whole business. There is a term for what they have, and it is a good old-fashioned term that has gone out of use. They have nerves or a nervous illness. It is an illness not just of mind or brain, but a disorder of the entire body. . . . We have a package here of five symptoms—mild depression, some anxiety, fatigue, somatic pains, and obsessive thinking. . . . We have had nervous illness for centuries. When you are too nervous to function . . . it is a nervous breakdown. But that term has vanished from medicine, although not from the way we speak. . . . The nervous patients of yesteryear are the depressives of today. That is the bad news. . . . There is a deeper illness that drives depression and the symptoms of mood. We can call this deeper illness something else, or invent a neologism, but we need to get the discussion off depression and onto this deeper disorder in the brain and body. That is the point.